Police say 31 year old William Oliver of Birmingham was killed after he was ejected from his car when it flipped over several times on Governors Drive.
It happened at 4:15 Sunday between Scenic Overlook Road and Cliff's Edge Circle near Monte Sano Boulevard.
Police say Oliver and his wife were traveling north when he apparently lost control of the car.
They were both transported to Huntsville Hospital, where Oliver died from his injuries.
His wife has non-life threatening injuries.
A car seat was seen on the side of the road, but officers say the couple's child was not in the car when it crashed.
Police Sergeant Marc Moon says speed does not appear to be a factor, but the investigation continues.